A Data center houses a large number of server computers, storage and etc in racks. With the rapid increase of heat generation rates per rack in a data center, energy consumption rates for cooling have been increased year by year. In this study, energy conservation effects of a MOA (multi-stage outdoor air enabled) cooling system in a data center has been investigated when it is applied to 5 different locations, Korea. As results, Energy conservation effects of the MOA cooling system was achieved at about 20% to 30%. Humidifier operation time was 40 to 55 days when supply air temperature was maintained at 13, and humidity condition was kept within the allowed range even though humidifier was off. Furthermore, humidification was not needed when supply air temperature was maintained at 25°C. In selected 5 locations in Korea, the difference of regional climatic conditions affected no more than 5% in cooling energy consumption rates.